Mervyn Maze qualified in Cape Town and after completing his house jobs spent several years in London as a Registrar at the Royal Free Hospital. He then spent just over 20 years at Stanford University in the USA before returning to London in 1999 as the Sir Ivan Magill Professor of Anaesthetics at Imperial College and Honorary Consultant in Anaesthesia at the Chelsea and Westminster Hospital.

Since 2000 Mervyn has also been Head, Department of Anaesthetics, Pain Medicine and Intensive Care, Imperial College and Deputy Head, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Imperial College, London.